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Sunday, July 12, 2020 | History

2 edition of Chemical induction of cancer found in the catalog.

Chemical induction of cancer

Joseph C. Arcos

Chemical induction of cancer

structural bases and biological mechanisms.

by Joseph C. Arcos

  • 322 Want to read
  • 16 Currently reading

Published by Academic Press in New York, London .
Written in English


Edition Notes

First edition by George Wolf.

Statement[by] JosephC. Arcos, Mary F. Argus [and] George Wolf.
ContributionsArgus, Mary F., Wolf, George.
ID Numbers
Open LibraryOL19743199M

In the s, the first pure chemical compounds, the polycyclic aromatic hydrocarbons (PAHs) benzo [a]pyrene, dibenz [a,h]anthracene, and 3-methylcholanthrene were shown to induce tumors in mice, firmly establishing defined chemical entities as a cause of cancer ( Cited by: Chemical Induction Of Cancer: Structural Bases and Biological Mechanisms Volume IIA deals with the organic and biochemical principles behind volume includes Part III of the work, which covers structure-activity relationships of chemica.

SUMMARY. PURPOSE: To test an experimental model of chemical mammary carcinogenesis induction in rats. METHODS: Twenty young virgin Sprague-Dawley female rats, aged 47 days, received 20 mg of 7,dimethylbenz(a)anthracene (DMBA) intragastrically by gavage. Afterwards, at 8 and 13 weeks, their mammary glands were examined. At the end of the . Written simply and clearly so that the experiments can be easily reproduced, the book presents Huggins’s experiments in the induction of breast cancer and leukemia in rodents. It also describes the methods he discovered to prevent cancer and to cure many of the cancers he has been able to induce.

Induction of apoptosis in MDA-MB breast cancer cells by a PARP1-targeting PROTAC small molecule Q. Zhao, T. Lan, S. Su and Y. Rao, Chem. Commun., , 55, Cited by: N-Nitrosodimethylamine (NDMA), also known as dimethylnitrosamine (DMN), is an organic compound with the formula (CH 3) 2 NNO. It is one of the simplest members of a large class of is a volatile yellow oil. NDMA has attracted wide attention as being highly hepatotoxic and a known carcinogen in lab g point: °C; °F; K.


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Chemical induction of cancer by Joseph C. Arcos Download PDF EPUB FB2

Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume I discusses the role of chemicals in the genesis of cancer in man. This book is organized into two parts encompassing four chapters that also present the concepts and techniques of testing chemicals for carcinogenic potential.

Chemical Induction of Cancer [George David Wolf, Alexander Haddow] on *FREE* shipping on qualifying offers. Chemical Induction of Cancer: George David Wolf, Alexander Haddow: : Books. Chemical Induction of Cancer: Structural Bases and Biological Mechanisms: Part B, Aliphatic and Polyhalogenated Carcinogens: Medicine & Health Science Books Format: Hardcover.

Chemical Induction of Cancer: Structural Bases and Biological Mechanisms Volume IIB deals with the organic and biochemical principles behind cancer. This volume includes Part III of the work, which covers structure-activity relationships of chemical carcinogens, the effect of chemical reactivity, molecular geometry, and metabolism on carcinogenic activity.

The past 25 years, since the appearance of the first volume of the predecessor series (1) authored by the Editors of this present volume, have seen an impressive number of studies on chemicals (and other agents) as etiologic factors in the induction of cancer.

Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume I discusses the role of chemicals in the genesis of cancer in man. This book is organized into two parts encompassing four chapters that also present the concepts and techniques of testing chemicals for carcinogenic Edition: 1.

Chemical Induction Of Cancer: Structural Bases and Biological Mechanisms Volume IIA deals with the organic and biochemical principles behind cancer. This volume includes Part III of the work, which covers structure-activity relationships of chemical carcinogens, the effect of chemical reactivity Book Edition: 1.

These may be referred to, in shorthand, as agents and processes: the causative agents (chemical, microbial, physical, environmental, and psychosocial) and the organismic processes, initiated and furthered by the agents, culminating in observable pathology (at the macromolecular, cytological, histological, organ function, locomotor, and behavioral levels).

Chemical Induction Of Cancer: Structural Bases and Biological Mechanisms Volume IIA deals with the organic and biochemical principles behind volume includes Part III of the work, which covers structure-activity relationships of chemical carcinogens, the effect of chemical reactivity, molecular geometry, and metabolism on carcinogenic activity.

Abstract. Cancer is one of the major causes of death in our society. It has been estimated that approximately 80% of all human cancers are of environmental origin. 1 This estimate is based primarily on epidemiological studies which show an enormous variation in the incidence of various forms of cancer is seen in different geographical areas of the by: 1.

Genre/Form: Laboratory Manual: Additional Physical Format: Online version: Wolf, George, Chemical induction of cancer. Cambridge, Mass., Harvard Univ. Press, COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle.

Chemical Induction of Cancer by George David Wolf,available at Book Depository with free delivery worldwide. Chemical Induction of Cancer Modulation and Combination Effects an Inventory of the Many Factors which Influence Carcinogenesis by Joseph C.

Arcos, Mary F. Argus, Yin-Tak Woo Published by Birkhäuser, Brand: Birkhäuser. Product No. A Azoxymethane (AOM) is a potent carcinogen used to induce colon cancer in rats and mice. It has been used in studies evaluating efficacy of preventative treatment for azoxymethane-induced carcinogenesis. 1,2,3 Azoxymethane is also commonly used to determine the chemopreventative effectiveness of particular foods such as undigestable sugars 4,5, red.

Animal Models of Chemical Carcinogenesis: Driving Breakthroughs in Cancer Research for Years Christopher J. Kemp PROTOCOLS 1 Induction of Liver Tumors in Mice with N-Ethyl-N-Nitrosourea or N-Nitrosodiethylamine Kay E.

Gurley, Russell D. Moser, and Christopher J. Kemp 2 Induction of Lung Tumors in Mice with Urethane. Evidence suggests that cancer is a disease of the genome at the cellular level. Interestingly, most agents that cause cancer (carcinogens) are agents that cause alterations to the DNA sequence or mutations (mutagens).

Thus, simi- larly to all genetic diseases, cancer results File Size: 2MB. Last 50 years of research has rendered some types of cancer curable, but still the major fear factor associated with this disease is unchanged. Animal models are classified according to the method of induction of cancer in the animal.

Spontaneous tumor models are the most primitive : Archana Chavan. cancer in humans and are sometimes called possible human carcinogens. Chloroform, DDT, formaldehyde, and polychlorinated biphenyls (PCBs) are examples of possible human carcinogens. Getting cancer from a chemical depends on the following: •The kind of chemical you were exposed to, •How much of the chemical you were in contact with.

Tobacco products contain a diverse array of chemical carcinogens that cause cancers of various types. To date, more than 60 carcinogens in cigarette smoke have been identified and evaluated by the International Agency for Research on Cancer [ 31 ].

Among them, tobacco-specific nitrosamines (such as NNK and NNN), Cited by:. Induction of cancer-specific cytotoxiciy towards human prostate and skin cells using quercetin and ultrasound Article (PDF Available) in British Journal of Cancer 92(3) .induction therapy listen (in-DUK-shun THAYR-uh-pee) The first treatment given for a disease.

It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation. When used by itself, induction therapy is the one accepted as the best treatment.Chemical induction of cancer modulation and combination effects an inventory of the many factors which influence carcinogenesis by Arcos, Argus, Woo starting at $ Chemical induction of cancer modulation and combination effects an inventory of the many factors which influence carcinogenesis has 0 available edition to buy at Half Price Books Marketplace.